Getting around by bus and coach La Crosse

Jefferson Lines bus company provides connections to Madison (3 hours), Milwaukee (4 hours) and Chicago (7 hours). In La Crosse, it picks up and drops off passengers at the Bus Depot, located at 314 Jay Street, about a ten-minute walk from the city's tourist office. The prices charged are more or less the same as at Greyhound, Jefferson Lines' main competitor in the Midwest. The buses are comfortable and usually have wifi and outlets. The vehicles are also equipped with restrooms.